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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0f6dd0df069916b5d690db8ae103c804ff9ce6f4c21bf12e5a84ec91279a048' 
  AND token = 'Ys5XM1xK1GnWWyqfsYH0tOjpZLKTWfEbdWC/1u3ZElY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}