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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfb3222f309c81a9e4f056f09f2f8ab3363c5c4b3ea292769aaedeedfdfca70c' 
  AND token = 'WBXrEQcVgp2+Lio7oKO3VpGo5vsyJhXvZtBCgmWRAQo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}