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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72af9658fec15e6a29265e1eafdc5c8bf1a90bdeebfdf345d85629b3555fbb08' 
  AND token = 'yXJAIEZ6C90HpOeEMDKbq5SGibYtfw/qAbYyeAzK+8M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}