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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d8b57fdd179fca95b4011b7319f32b9427dfb985c80688bec15df8a61bf9acf' 
  AND token = 'vwZEV4b5BOR2PgqtZAD9lI7wOF4pweq5nPcDVceqhP8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}