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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb4e45b2758cbc32feb6f5b628429a89b735db723c3a68b335af1bc9be1c731d' 
  AND token = '3vbdhv/z8QUqscOV02GNJoV1bA3SEYFYDIylaXKWbcA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}