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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33eecd55a872f01ea435c4130d58bdca50c13aae284562f8bdd83d8a42422a15' 
  AND token = 'ibTSQrLE2+X9i5LEBn2tawEEZaOXVE0/LOU90Lk7oSk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}