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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e021b2b4263d2000b489a5849dffdbc7f8e430c786b785383e63d8bae3ec012' 
  AND token = '/b7QbjOf2JiHSVqs6N7p9gyV6VBOVP8YpYLr4IJYp3I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}