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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4417ec409ecce87463fd6f31dd145299011388db1c3e3dabd5111a8ff5b894c8' 
  AND token = 'rd3QKhxWzSEi2SxLta9vFRmdOoT5cwT2HUSASihuZwU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}