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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bc8117d6041f54e8336b6f3416f9f90e576d897f9e0d1782d6e105b921f390c' 
  AND token = 'Si/L7nR8yWz/CAMd4BY0zE16b3BKPT357uc68VMrKuU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}