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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '716f51e52a239799dd3fe81e0a2b930ae05559defd43ab3a4fa0ebfbd0f31bda' 
  AND token = 'GXVW1KgrpJEWTsLukFpBuKpTks9akeO4g9L8mw159lE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}