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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59ce69b5f0fe6e20f30d10a2c88a38fa332f999803fc54520fe424ff66bb561f' 
  AND token = 'dBLj5b3iH7/Knr5P6zgJ7c1a+aVkImLXWctusA9ElJ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}