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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4952fddd0a880383b1143b5226b4098a2200d1b2a9e8f8d51389e73816602b76' 
  AND token = 'LVsYJaX1HL3Mo6/9rBbLrqA4y1ioov8eHI64ux8XAA8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}