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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06e9068e24bc63e2c9d473eb09f167429b70cdfc8c3587124054100ef5b0b5c3' 
  AND token = 'zzAzxhZskeP9DjYMr6TtZu8Mpapi+YQa0pMR5t5MBYU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00009

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}