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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3fb95f49c29fa682c76032629fa54bc34815879fa9f4b749b30366559126043d' 
  AND token = 'pkUSSrt2thkga4dn3PiLZYOqqXJn96SXBLBgXo9ZESE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}