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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '511105888b9ce6f6469b4177331aa9abd9b0a711648cf14dc752303d9da5aeff' 
  AND token = 'a5vUJoImLcP4Co+6FnCy+awHh0j1Ivw9rRtpiolVOVk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}