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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5538139ebb1927b4654ae4050d86a0b6c51b22af9fd14919a4d47b3a1fa76f6f' 
  AND token = 'dEJ6Q/toZHxn8t9ElaJVrug9RPgWcZpFXCWtRnrMnbs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}