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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ddc6a9678e0f14ae43fa28722ab00acac57a54e10ccbb4c64ff82f7099ce7167' 
  AND token = 'DHt0lOCuqoyRbKIwAIveNRyYHpUyGd2kADsThRT6Ayk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}