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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4c429d9e2e0ffe73ba9aabb9048fd4bd2f59ded68953f25f2bf3cc710baaadc' 
  AND token = '+B4H3UombUH/6/4h6r/jXLCeQVVyy/rtN3SWHLS3Bks=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}