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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fabe49b77364d171458c3a8baef053859a125e7a6bd56b1a8ce768dffe9f00a5' 
  AND token = 'Q+DnnTa13p+jC56OW4UyTVFRk/WlX6pELoA5kwGDM00=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}