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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18501c69354aadaab27274da6085194e06230d3e8c08e407e78cf40d2a5b290b' 
  AND token = 'OMu0Bx16dOlxy0gg7RbGtHguCDETV8F7t5HY2w8npe8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}