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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28227a2e6f18e7ef5cd1c4b5b418bfefbc6a81b115156e1e2c93567832dbc0b9' 
  AND token = 'nuFkhrDqek3SnDwPcrVBQSVhKVS51CfesiTWQo4ssGc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}