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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c485859042469a997939725e80be00d86af4daf0f0e3bab68577f5f19494a83b' 
  AND token = 'sWdrXEUN35cd3zcCBVPlJEzwi+r3BKJI+pMZlth0Z8M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}