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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '645001f0ca8cf147b83b1936e2c01830ebcb5c855dc930b1fc5a96ec87779f3a' 
  AND token = 'XnyaZ++yZr7KrpD2r+pGiK2Bazw0BocmavuCCSIxvko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}