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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb9e185ddb14de492246d1695c94ace1ade4b04c55d0b8bfde7aa276ff38a36c' 
  AND token = 'WMiLgnPgyb7+dkD0kFDmYoFfIQDw6bkwMPuQ5AHeAp0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}