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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d721f0b630ac719fa3db5ea2cf9b9a1b262ef832e862104b442a2a0fe763d16' 
  AND token = 'MiEsVU2FCBGpKiaFRAKi1hF6AbgodlP11oHFB5vWIQU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}