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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a5d0e9a32eba2f77964dad823ae66a11d751bafcdd5e1c947297604c8f9dc3c' 
  AND token = 'UlBACtMYLBQ9iP5Wx/JQLxm/W2YN3y5g28w4bzt6NS0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}