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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0ae50e45875fa29bf5f87e25e38857347133f81518c2f0771f540d81f6f22c1' 
  AND token = 'Y9z4P5Q4ift1uzwN+AjuFo+odMW65qCpuyv38Ex+Eqs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}