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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e8b844d87d9793af85e7e0c2990100edd40f7dba5b727bf62a2699a5e45fc72' 
  AND token = 'BXWFp8EJLhJGZCleYeD1mLyk8loPuEqfrpXTs78Bssc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}