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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4594e6d4b5c40b24700d044e3b1890e45f85a276980dee3d06e92a6838ecaf72' 
  AND token = 'cdt/KBwkOZ3/yITP3S5LgxjIVU+ptQOriYaOAmMQUZ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00008

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}