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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3567a5a54e0ecf6a0fc3bdde97aa5a173403befc5d042ac017cc10552a90efd1' 
  AND token = 'VQSx1Xn+bajkfZHoGEx7/B1BPdOI8FKPSHHMJWo2bFo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}