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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b586aa68c18373e490c0a8ff75c148fdd119b457d6aecfc9a1dfa13eddd68e63' 
  AND token = 'BWqqoJxeiBHJjc9gS0zT+rxCiMOxA94GRl2WPL6nMgs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}