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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '320901caf925ec3975dc0f5bdaec5f809d1dc710ece36918f2904043c6f3dbf9' 
  AND token = 'H5CT90LyE5LupSzQzKfi1X0Q906ltOEJGW3v0p+LMmE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}