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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fdf8c1a8a69b9e84a09f7931aa1d295135e1e83268d9a833b6e9497ef4e49af7' 
  AND token = 'a+Xns6UDRiVod+KPiggQsE3Xt6Q7GHlFbDn7bgyQO6U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}