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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44b9e368c05f5a94b81598f331581ba75294fc6372e1273886ab3a5503594ce1' 
  AND token = 'Aj91JH9+Q8C8MCN9K0xfyAzOVoa9Rc8ApsvXr7hoiy4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}