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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ab25a791db5a18974c985d6703f009cbe1250e6799adfb49159e17d28430861' 
  AND token = 't6ZxNbn8+O9nVaqWex2QV9SyGIMx4w8d3heNwOZsFs4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}