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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9130eeec53c99f4255aad8a85855d48cf6ee7672fd965117f295cfe645d9c39' 
  AND token = 'BGiP4IQloYD4E+td1dOTV0CCeVjWGNliuhbR6MxroYo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}