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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ed8f9e0e76eaea8705c0b6a71825da7f5bc03b79203ae2eb40d18a316949df7' 
  AND token = 'QtZduRx1ryDPyV/0aWfW304fHtdbc2Y13+f2OSejuA4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}