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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '642237f897f1ed8f538b90a1d31332a8b29d90fabd061002661e29dad9ef4819' 
  AND token = 'SJz1Z+jFv6kvxWFPyiR8C3iIQNx2wng58ZkA65S8O2Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}