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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4229643c5117fd1a2976ce88f34f630cd67fad9d68c2acf8e049d1e1e3257da9' 
  AND token = 'bTBQbES7ox3tHVERBSkM6Pyxy733UakBLPU98Z0XL5k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}