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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '800bfd99696184bb39deca524c371831dec539022304466cdf072548a922a292' 
  AND token = '78hISq19wk4/WPbDnoDwqDT8uBh1MmuskRcMTFbGVYg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00011

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}