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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53b1f4907d72cbaf4ff5998697a786b299b254fe684449afe5186b173b2f4b4e' 
  AND token = 'b3/yj9KByy3oxo4RuKUjBVkAc/76Kij4cTYcPLLYBKo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}