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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b277dc4e35a543391c55dd7d2fc00b3e803c08b63c3a4739735c67fa41167de2' 
  AND token = 'hAMVG+Lc0mQcPkYVXcrrXvPFLvviVMG8MGuUX4gxBL0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}