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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc49d2b38e7cde110c1a43791a99e6e70d80df2e432738c506cefb1823e72ac7' 
  AND token = 'x7SCAIo7+yWWdUfQXoP/dWVhNcSOsOggmlPXSVjytMQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00011

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}