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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1a6c6c85e3d3eb270a8ae582a48504527e549b3bbfb9b74e448fabc962d8a46' 
  AND token = 'thamOhSSfHRx5/Naqu9nr2gDY9QBFFfDpLZN8wKSjwE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}