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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45a261984913f15825768270272322268a702991c7419bd2193d4e9c32228f7b' 
  AND token = 'uum+fS6iS1cM+cVbOyVZrarxQdmsiAb1pXQMsElI0S8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}