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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2144f9d67c722ff3d3e0836005459edd0c44a08909c0cb60cd0301df2d94e00c' 
  AND token = 'PSpiVIfHIO/okF/o/djpOEFmmarqRSbxNzHseqZbCRM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}