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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74465452f52fd07e57e08ad3f5b04028009a64b515cb1604a8cc74bbe9abca5a' 
  AND token = 'EAvQEIhlMmBMRU4c20dgbo0IkK4iNyelq0R0CoYSy30=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00011

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}