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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be8ccabe09b915a7bab2e86f9c49c65eba18bd80ebbf7a6fcb4f4687e99bb0cf' 
  AND token = '/+in/RNcTrxEypSkGEz0w+xAVYf36T/Ri7ZQNSXbBXM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}