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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6742fd83552e90d92a1d69fa8326c0dbeb15c9dd9173395c64132d3b0245cf5' 
  AND token = 'WVpDDL14H5vTnRfUGbxEfFnpC2vHme+JaLuPvLs9dNg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}