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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77fe4a8ca1128b05bebc38411d1505e9b635b72fc154d82591294196b5a053a6' 
  AND token = '8y4meK9gvdbZtDFqzSJ/RBaW1JOxxf35k6cM0152qC0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}